2026 MDS-ES Yakatarisana Musangano
Parkinson's Disease Decoded: Genes, Environment, uye Epidemiological Challenge

Joinha nyanzvi dzinotungamira mumunda kuti uongorore kupindirana kwakaoma kweiyo genetics, kuratidzwa kwezvakatipoteredza, uye ari kubuda epidemiological maitiro muParkinson's disease (PD).

Kuburikidza nemusanganiswa wehurukuro dzeplenary, nhaurirano dzepaneru, uye zviratidziro zvisinganzwisisiki, iwe uchawana nzwisiso yakakosha muiyo biological, molecular, uye kiriniki zviyero zvePD, pamwe nematambudziko ekushandura mukuongororwa, kurapwa, nekudzivirira.

Kunyoresa paindaneti kwavharwa.
udza mashoko Dzidzo@movementdisorders.org nemibvunzo.

 

Mashoko Okuzarura

David Burn, Mutungamiri weMDC,
Jean-Christophe CorvolSachigaro weMDS-ES,
Enza Maria ValenteSachigaro weSainzi Program,
Christine Klein, Sachigaro weKuronga weMunharaunda
13: 00 - 13: 15

 

Chikamu 1: 
Chirwere cheParkinson: ngano yekuwedzera kuoma
Sachigaro: Jean Christophe Corvol, MDS-ES Chair (Paris, France)
13:15 - 15:15

Epidemiology yechirwere cheParkinson: Iri idenda idzva here?
Yoav Ben-Shlomo (Bristol, United Kingdom)

Sei miedzo yakawanda yePD ichikundikana? Matambudziko azvino mukusarudzika kwevarwere uye modhi-kune-munhu shanduro 
Margherita Fabbri (Toulouse, France)

Kukurukurirana kwePaneru 

Mashoko Okuvhara
Jean-Christophe Corvol (Paris, France)

Chikamu 2:
Main genetic determinants muParkinson's disease
Yakapihwa mukubatana neEuropean Academy yeNeurology (EAN)
Sachigaro: Christine Klein (Lubeck, Germany)
15: 15 - 17: 15

Kuitika kwepasirese, mutational spectrum uye phenotypes yeParkinson's disease majini 
Enza Maria Valente (Pavia, Italy)

Genetic uye zvakatipoteredza modifiers yeLRRK2-PD
Joanne Trinh (Luebeck, Germany) 

Multilevel modulation yeGBA kupinda 
Rosanna Asselta (Milan, Italy)

Kukurukurirana kwePaneru

Chikamu 3:
MDS-ES & EAN Joint Session: Clinical, Imaging, uye Therapeutic Aspects of Genetic Parkinson's Disease.
Sachigaro: Alessandro Tessitore, Co-Chair, EAN Scientific Panel paMovement Disorders
17: 15 - 19: 30

Rare mafomu e genetic Parkinson's: maitiro
Kailash Bhatia (London, United Kingdom)

Neuroimaging biomarkers uye kukanganisa kwe genetics
Irena Rektorova (Brno, Czech Republic)

Impact ye genetics mune neuromodulation therapy muParkinson's zvirwere
Elena Moro, (Grenoble, France)

Kukurukurirana kwePaneru

European Academy yeNeurology (EAN) Ruzivo uye Mikana 
Mutungamiri weEAN  

Event:
Welcome Welcome
19: 30 - 20: 30

Zvinwiwa uye zvinwiwa zvakapfava zvichapihwa.

Chikamu 4:
Genome-wide kuoma kweParkinson's disease ngozi
Sachigaro: Thomas Gasser (Tübingen, Germany)
8: 00 - 10: 30 

Maitiro matsva ekurwisa chirwere cheParkinson genetics
Christine Klein (Luebeck, Germany)

PD-GWAS uye genome-wide determinants of phenotypic maitiro
Huw Morris (London, United Kingdom)

Epigenetic modifiers
Lasse Pihlstrom (Oslo, Norway)

Kukurukurirana kwePaneru 

Chikamu 5:
α-synuclein-mediated nzira dzechirwere
10: 30 - 12: 30
Sachigaro: Daniela Berg (Kiel, Germany)

Pathological α-synuclein uye mitochondrial kukuvara
Tommaso Schirinzi (Rome, Italy)

Transcriptomic siginecha mu synucleinopathies
Mina Ryten (London, United Kingdom)

Dysfunction ye clearance systems uye α-synuclein toxicity
Friederike Zunke (Erlagen, Germany)

Kukurukurirana kwePaneru

Plenary Lecture:
Kuno kutsanangudzo yebiological yeneuronal uye glial synucleinopathies 

Sachigaro: Enza Maria Valente (Pavia, Italy)
12: 30 - 13: 15
Guenter Hoglinger (Munich, Germany)

Poster Session / Oral Platform Mharidzo
Sachigaro: Roberto Erro (Salerno, Italy)
13: 45 - 14: 55

Chikamu 6:  
Zvinhu zvakatipoteredza uye mararamiro
Sachigaro: David Burn, Mutungamiri weMDS (Galway, Ireland)
15: 00 - 17: 00

Mishonga yezvipembenene uye kusvibiswa kwemhepo muParkinson's disease ngozi
Alastair Noyce (London, United Kingdom)

Modifiable zvakatipoteredza zvinhu: fodya, kudya uye nezvimwe
Alexis Elbaz (Paris, France)

Kubatanidza exposome uye metabolome kuona magadzirirwo ezvakatipoteredza mune genetic Parkinson's chirwere 
Emma L. Schymanski (Luxembourg)

Kukurukurirana kwePaneru 

Chikamu 7:
Zvirwere zveParkinson's comorbidities
Sachigaro: Pille Taba (Tartu, Estonia)
17: 30 - 19: 00

Chirwere cheshuga uye insulin-resistant
Mutauri TBD

kenza
Tiago Outeiro (Gottingen, Germany)

Kukurukurirana kwePaneru 

Plenary Lecture:
Kushandisa muviri uye uropi: A neuroscientific maonero
Sachigaro: Roberto Erro (Salerno, Italy)
19: 00 - 19: 45    
Bas Bloem (Njimegen, The Netherlands)

Chikamu 8:
Mhirizhonga pakati pehura nehuropi
Sachigaro: Cristian Falup-Pecuariu (Brasov, Romania)
8: 30 - 10: 30

Iyo gut-brain axis
Per Borghammer (Aarhus, Denmark)

Chirwere cheParkinson dysbiome chinokonzeresa neurodegeneration mumakonzo
Sandra Morais Cardoso (Coimbra, Portugal)

Microbiota-yakavakirwa kupindira kurapa chirwere cheParkinson
Filip Scheperjans (Helsinki, Finland)

Kukurukurirana kwePaneru

Chirongwa chePosita 2
10: 00 - 10: 30

Chikamu 9:
Kuzvimba uye kusadzivirirwa
Sachigaro: Brit Mollenhauer (Gottingen, Germany)
11: 00 - 12: 30

Kuzvimba kwehuropi mukati mezvirwere zve neurodegenerative
Michael T. Heneka (Luxembourg)

Modulation yekuzvimba mune alpha-synuclein mbeva modhi)
Vania Broccoli (Milan, Italy)

Basa re lipid dysregulation mune neuroinflammation uye maitiro ekurapa
Per Svenningson (Stockholm, Sweden)

Kukurukurirana kwePaneru 

Plenary Lecture:
Artificial intelligence-based stratification yeParkinson's disease trajectories
Sachigaro: Esther Cubo (Burgos, Spain)
12: 30 - 13: 30
Holger Fröhlich (Bonn, Germany) 

Mashoko Okuvhara
Jean Christophe Corvol, Enza Maria Valente, Per Svenningsson

1. Ongorora ikozvino epidemiological maitiro muchirwere cheParkinson, kusanganisira kukwira kwepasi rose kwezviitiko uye izvo zvakasiyana-siyana zvinopa kupararira kwayo.

2. Ongorora iwo makuru genetic anobatsira kuPD, kusanganisira basa remonogenic mutations uye genetic risk factors (eg, LRRK2, GBA), iyo inozivikanwa modifiers yekupinda uye pesvedzero yemajini-zvakatipoteredza kusangana.

3. Kurukurai kukosha kwezvidzidzo zvegenome-wide association (GWAS), epigenetic maitiro, uye data yezvinyorwa mukufambisira mberi nzira dzekurapa dzePD.

4. Nzwisisa basa repathogenic realpha-synuclein, kusanganisira kudyidzana kwayo nekukuvara kwemitochondrial, mapuroteni clearance masisitimu, uye kukosha kwayo kune glial uye neuronal dysfunction.

5. Ongorora gut-brain axis uye microbiota-based therapies seminda iri kubuda muPD pathogenesis uye nzira dzekupindira.

6. Ongorora mabasa euroinflammation uye immune immune, nekutarisa kune lipid metabolism uye yakanangwa yekurapa mikana.

7. Nyatsoongorora kushandiswa kweuchenjeri hwekugadzira mukugadzirisa nzira dzechirwere uye kuvandudza mhando dzekutarisira dzechirwere cheParkinson.