Spasticity
Clinical Overview
Spasticity chinhu cheakasiyana neurologic mamiriro nekuda kwekurasikirwa kwekudzivirirwa kwemotor neurons. Ikiriniki inopa kusanganiswa kwakasiyana-siyana kwekuoma mitezo, kuwedzera tendon reflex basa (hyperreflexia ine brisk reflexes uye chiratidzo chakanaka cheBabinski) uye hypertonia (kusiyana nekuoma kunoonekwa sechimiro chechimiro cheparkinsonism). Clonus (kazhinji kacho mumakumbo) inogona kunge iripo uye inopa sekuzvidira, rhythmic, muscular contractions uye kuzorora.
Pathophysiologically, kutambanudza reflex kunogona kuita basa rinokosha mukusaenzana pakati pezvinofadza uye zvinodzivisa kupinza kune α motor neurons.
Zvinowanzokonzera spasticity zvinosanganisira kukura kana kuwanikwa maronda epiramidhi turakiti muuropi uye / kana musana wemuzongoza mumamiriro ezvinhu ecerebral palsy, sitiroko, multiple sclerosis, trauma, nezvimwe.
Ona tsananguro yakazara
Spasticity chinhu chakajairika uye chakakosha chikonzero chekuderedzwa kwehupenyu uye kuzvimirira. Kudonha ndeimwe yemhedzisiro yakakosha (onawo: gait disorders).
Ongororo uye manejimendi e spasticity inofanirwa kutanga yatarisa kusasanganisa zviratidzo zvinokonzeresa. Mushure mekugadziriswa kwezviratidzo zvinokonzeresa, manejimendi anowanzo tsigira asi anogona kusanganisira zvemuviri uye zvebasa. Mishonga chaiyo inogona kuvandudza inosanganisira GABA receptor agonists, semuenzaniso baclofen kana benzodiazepines, eg clonazepam, kana ryanodine receptor anatagonists, eg dantrolene kana botulinum toxin.
2026 Yakapedzisira kuongororwa neBhodhi reVanyori veWebhusaiti
2016 Update Inopihwa na:
Susanne A. Schneider, MD
Consultant Neurologist
LMU University Hospital Muenchen
Munich, Germany
